BAKER BROS. ADVISORS LP

MDGL

BAKER BROS. ADVISORS LP serves as an insider at Madrigal Pharmaceuticals, Inc. (MDGL). This page tracks their complete SEC Form 4 insider trading history including stock purchases and sales.

Total Buys

26 trades

$1.25B

Total Sells

0 trades

$0.00

Net Position

Net Buyer

$1.25B

Companies Traded

KYMR, KALA, MDGL, ACAD

Active Period

Jun 2021 – Dec 2025

26 total trades

Most Recent

Buy KYMR

Dec 11, 2025 · $172.50M

BAKER BROS. ADVISORS LP's Insider Trading at Madrigal Pharmaceuticals, Inc. (MDGL)

Buys

5 · $602.75M

Sells

0 · $0.00

Total Shares Bought

3,130,475

Total Shares Sold

MDGL Price Chart

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Date	Type	Shares	Avg Price	Value	Shares After
Mar 25, 2024↗	Buy	1,057,692	$260.00	$275.00M	2,493,600
Dec 14, 2023↗	Buy	136,370	$220.47	$30.07M	1,793,400
Nov 21, 2023↗	Buy	131,429	$183.18	$24.08M	1,667,100
Nov 15, 2023↗	Buy	156,886	$150.50	$23.61M	1,545,780
Oct 5, 2023↗	Buy	1,648,098	$151.69	$250.00M	1,522,650

BAKER BROS. ADVISORS LP's Insider Trading at Incyte Corporation (INCY)

Buys

4 · $286.35M

Sells

0 · $0.00

Total Shares Bought

4,108,777

Total Shares Sold

INCY Price Chart

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Date	Type	Shares	Avg Price	Value	Shares After
Mar 10, 2022↗	Buy	389,080	$72.24	$28.11M	33,419,100
Feb 22, 2022↗	Buy	525,804	$67.96	$35.73M	33,039,600
Feb 14, 2022↗	Buy	1,598,374	$66.91	$106.95M	32,531,500
Dec 17, 2021↗	Buy	1,595,519	$72.43	$115.56M	30,932,700

BAKER BROS. ADVISORS LP's Insider Trading at Kymera Therapeutics, Inc. (KYMR)

Buys

3 · $201.34M

Sells

0 · $0.00

Total Shares Bought

2,661,314

Total Shares Sold

KYMR Price Chart

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Date	Type	Shares	Avg Price	Value	Shares After
Dec 11, 2025↗	Buy	2,005,813	$86.00	$172.50M	7,955,920
Jun 30, 2025↗	Buy	655,500	$44.00	$28.84M	6,117,300
Aug 22, 2024↗	Buy	1	$46.41	$46.41	5,516,990

BAKER BROS. ADVISORS LP's Insider Trading at Kodiak Sciences Inc. (KOD)

Buys

12 · $137.56M

Sells

0 · $0.00

Total Shares Bought

3,280,555

Total Shares Sold

KOD Price Chart

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Date	Type	Shares	Avg Price	Value	Shares After
Jun 6, 2022↗	Buy	572,349	$7.77	$4.45M	15,967,500
May 27, 2022↗	Buy	350,406	$6.75	$2.36M	15,455,500
May 18, 2022↗	Buy	456,690	$5.91	$2.70M	15,142,100
Feb 17, 2022↗	Buy	400,965	$54.45	$21.83M	14,735,000
Jan 31, 2022↗	Buy	347,665	$52.02	$18.08M	14,364,500
Jan 25, 2022↗	Buy	501,111	$57.49	$28.81M	14,027,800
Oct 1, 2021↗	Buy	86,932	$95.83	$8.33M	13,526,700
Sep 17, 2021↗	Buy	31,838	$94.39	$3.01M	13,301,000
Sep 9, 2021↗	Buy	57,501	$93.31	$5.37M	13,269,200
Aug 19, 2021↗	Buy	114,396	$87.50	$10.01M	13,211,700
Aug 13, 2021↗	Buy	102,773	$87.19	$8.96M	13,097,300
Jun 30, 2021↗	Buy	257,929	$91.72	$23.66M	12,994,500

BAKER BROS. ADVISORS LP's Insider Trading at ACADIA Pharmaceuticals Inc. (ACAD)

Buys

1 · $22.71M

Sells

0 · $0.00

Total Shares Bought

896,522

Total Shares Sold

ACAD Price Chart

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Date	Type	Shares	Avg Price	Value	Shares After
May 24, 2023↗	Buy	896,522	$25.33	$22.71M	39,317,700

BAKER BROS. ADVISORS LP's Insider Trading at KALA BIO, Inc. (KALA)

Buys

1 · $2.00M

Sells

0 · $0.00

Total Shares Bought

310,559

Total Shares Sold

KALA Price Chart

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Date	Type	Shares	Avg Price	Value	Shares After
Dec 31, 2024↗	Buy	310,559	$6.44	$2.00M	1,083,400

Related Insiders

Jeremy G Chadwick

officer: Chief Operating Officer

KYMRSell · Mar 11, 2026

Carole Huntsman

officer: Chief Commercial Officer

MDGLSell · Mar 6, 2026

Mardi Dier

officer: EVP and CFO

MDGLSell · Mar 6, 2026

William John Sibold

director, officer: President and CEO

MDGLSell · Mar 6, 2026

Rebecca Taub

director

MDGLSell · Mar 6, 2026

Shannon T Kelley

officer: General Counsel

MDGLSell · Mar 6, 2026

Bruce N. Jacobs

officer: Chief Financial Officer

KYMRSell · Mar 4, 2026

Jared Gollob

officer: Chief Medical Officer

KYMRSell · Mar 4, 2026

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