ALNY
HealthcareAlnylam Pharmaceuticals, Inc.
$313.45-3.77 (-1.19%)
Prev Close
$317.23
Open
$319.00
High
$319.50
Low
$309.92
Volume
526.0K
Market Cap
$42.07B
P/E
155.95
Div Yield
—
Over the past 12 months, insider activity at Alnylam Pharmaceuticals, Inc. (ALNY) has been exclusively selling, with 0 insider purchases totaling $0.00 and 51 insider sales totaling $129.04M. The most recent insider transaction was by Fitzgerald Kevin Joseph (officer: CSO & EVP, Head of Research), who sold $417.7K worth of shares on Mar 6, 2026. Alnylam Pharmaceuticals, Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $42.07B.
Buys (12M)
0
$0.00
Sells (12M)
51
$129.04M
Net Activity
Net Seller
$129.04M
Active Insiders
9
last 12 mo
ALNY Price Chart
ALNY Insider Trading Activity
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Mar 6, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 1,291 | $323.54 | $417.7K | 21,831 |
| Mar 6, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 4,713 | $323.53 | $1.52M | 23,300 |
| Mar 6, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 2,933 | $323.08 | $947.6K | 98,493 |
| Mar 6, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 2,468 | $323.08 | $797.4K | 64,159 |
| Mar 6, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 2,309 | $323.08 | $746.0K | 36,500 |
| Mar 4, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 6,500 | $323.62 | $2.10M | 25,063 |
| Mar 4, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 6,984 | $323.63 | $2.26M | 26,848 |
| Mar 4, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 13,598 | $327.65 | $4.46M | 105,227 |
| Mar 4, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 4,412 | $327.65 | $1.45M | 66,414 |
| Mar 4, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 3,196 | $327.65 | $1.05M | 38,157 |
| Mar 2, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 4,627 | $331.34 | $1.53M | 26,629 |
| Feb 17, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 4,000 | $321.25 | $1.28M | 23,305 |
| Feb 17, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 2,242 | $310.08 | $695.2K | 24,848 |
| Feb 17, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 13,916 | $310.08 | $4.32M | 85,662 |
| Feb 17, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 2,242 | $310.08 | $695.2K | 59,802 |
| Feb 17, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 1,959 | $310.08 | $607.4K | 31,769 |
| Feb 12, 2026↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 4,000 | $321.25 | $1.28M | 0 |
| Feb 12, 2026↗ | Garg Pushkal | EVP Chief R&D | Sell | 2,242 | $310.08 | $695.2K | 0 |
| Feb 12, 2026↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 2,242 | $310.08 | $695.2K | 0 |
| Feb 12, 2026↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,959 | $310.08 | $607.4K | 0 |
| Jan 14, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 3,740 | $367.35 | $1.37M | 25,025 |
| Jan 14, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 1,469 | $362.74 | $532.9K | 23,982 |
| Jan 14, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 9,459 | $362.71 | $3.43M | 87,741 |
| Jan 14, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 2,704 | $363.06 | $981.7K | 60,173 |
| Jan 14, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 1,450 | $362.57 | $525.7K | 31,199 |
| Jan 11, 2026↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 3,800 | $367.37 | $1.40M | 0 |
| Jan 11, 2026↗ | Garg Pushkal | EVP Chief R&D | Sell | 1,510 | $362.87 | $547.9K | 0 |
| Jan 11, 2026↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 9,577 | $362.87 | $3.48M | 0 |
| Jan 11, 2026↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 2,780 | $362.87 | $1.01M | 0 |
| Jan 11, 2026↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,510 | $362.87 | $547.9K | 0 |
| Nov 26, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 1,121 | $445.12 | $499.0K | 0 |
| Nov 17, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 12,128 | $452.18 | $5.48M | 0 |
| Nov 12, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 25,650 | $452.75 | $11.61M | 0 |
| Oct 1, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 2,441 | $452.05 | $1.10M | 0 |
| Oct 1, 2025↗ | Garg Pushkal | EVP Chief R&D | Sell | 5,959 | $451.76 | $2.69M | 0 |
| Oct 1, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 8,924 | $452.05 | $4.03M | 0 |
| Oct 1, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 3,821 | $452.05 | $1.73M | 0 |
| Oct 1, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,405 | $452.05 | $635.1K | 0 |
| Sep 9, 2025↗ | Reitan Colleen F | Director | Sell | 18,000 | $467.60 | $8.42M | 0 |
| Aug 29, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 3,474 | $448.37 | $1.56M | 0 |
| Aug 18, 2025↗ | BONNEY MICHAEL W | Director | Sell | 11,250 | $450.00 | $5.06M | 0 |
| Aug 15, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 1,396 | $453.27 | $632.8K | 0 |
| Aug 15, 2025↗ | Garg Pushkal | EVP Chief R&D | Sell | 2,851 | $455.89 | $1.30M | 0 |
| Aug 15, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 6,979 | $453.27 | $3.16M | 0 |
| Aug 15, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 2,274 | $453.27 | $1.03M | 0 |
| Aug 15, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,396 | $453.27 | $632.8K | 0 |
| Aug 14, 2025↗ | Ausiello Dennis A | Director | Sell | 31,448 | $436.58 | $13.73M | 0 |
| May 30, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 50,937 | $305.00 | $15.54M | 0 |
| May 15, 2025↗ | BONNEY MICHAEL W | Director | Sell | 11,250 | $277.71 | $3.12M | 0 |
| Mar 24, 2025↗ | PYOTT DAVID E I | Director | Sell | 7,440 | $299.00 | $2.22M | 0 |
| Mar 21, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 9,766 | $293.36 | $2.86M | 0 |
| Mar 3, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 2,755 | $242.94 | $669.3K | 0 |
| Mar 3, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 2,557 | $242.92 | $621.1K | 0 |
| Mar 3, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 3,877 | $243.79 | $945.2K | 0 |
| Mar 3, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,264 | $243.78 | $308.1K | 0 |
| Mar 3, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 471 | $243.78 | $114.8K | 0 |
| Feb 28, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 496 | $241.69 | $119.9K | 0 |
| Feb 27, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 935 | $241.69 | $226.0K | 0 |
| Feb 27, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 2,900 | $241.69 | $700.9K | 0 |
| Feb 27, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 796 | $241.70 | $192.4K | 0 |
| Feb 27, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 513 | $241.68 | $124.0K | 0 |
| Feb 13, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 2,103 | $252.71 | $531.4K | 0 |
| Feb 13, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 3,109 | $253.43 | $787.9K | 0 |
| Feb 13, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 1,213 | $255.17 | $309.5K | 0 |
| Feb 13, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 967 | $255.17 | $246.8K | 0 |
| Jan 27, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 52,592 | $285.00 | $14.99M | 0 |
| Jan 23, 2025↗ | SHARP PHILLIP A | Director | Sell | 11,250 | $275.00 | $3.09M | 0 |
| Dec 12, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 1,752 | $251.00 | $439.8K | 0 |
| Nov 25, 2024↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 3,000 | $251.65 | $754.9K | 0 |
| Nov 25, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 1,682 | $250.98 | $422.1K | 0 |
| Nov 25, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 5,219 | $250.98 | $1.31M | 0 |
| Nov 25, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,682 | $250.98 | $422.1K | 0 |
| Nov 25, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,469 | $250.98 | $368.7K | 0 |
| Aug 29, 2024↗ | Reitan Colleen F | Director | Buy | 36 | $287.85 | $10.4K | 0 |
| Aug 29, 2024↗ | Reitan Colleen F | Director | Sell | 36 | $232.86 | $8.4K | 0 |
| Aug 20, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 15,000 | $280.00 | $4.20M | 0 |
| Aug 12, 2024↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 22,025 | $270.99 | $5.97M | 0 |
| Aug 6, 2024↗ | Ausiello Dennis A | Director | Sell | 20,250 | $262.00 | $5.31M | 0 |
| Aug 1, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 15,148 | $270.00 | $4.09M | 0 |
| Jul 11, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 7,093 | $261.00 | $1.85M | 0 |
| Jun 25, 2024↗ | SCHULMAN AMY W | Director | Sell | 8,500 | $240.00 | $2.04M | 0 |
| Jun 24, 2024↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 1,198 | $230.99 | $276.7K | 0 |
| Jun 24, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 2,103 | $230.99 | $485.8K | 0 |
| Jun 24, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 8,301 | $230.99 | $1.92M | 0 |
| Jun 24, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,605 | $231.00 | $370.7K | 0 |
| Jun 24, 2024↗ | PYOTT DAVID E I | Director | Sell | 32,450 | $220.69 | $7.16M | 0 |
| Jun 24, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,605 | $231.00 | $370.7K | 0 |
| May 29, 2024↗ | SCHULMAN AMY W | Director | Sell | 21,700 | $148.60 | $3.22M | 0 |
| Feb 29, 2024↗ | SHARP PHILLIP A | Director | Sell | 30,000 | $151.34 | $4.54M | 0 |
| Feb 27, 2024↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 329 | $155.30 | $51.1K | 0 |
| Feb 27, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 574 | $155.30 | $89.1K | 0 |
| Feb 27, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 2,932 | $155.31 | $455.4K | 0 |
| Feb 27, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 574 | $155.30 | $89.1K | 0 |
| Feb 27, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 501 | $155.30 | $77.8K | 0 |
| Feb 15, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 1,308 | $148.06 | $193.7K | 0 |
| Feb 15, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 7,030 | $148.06 | $1.04M | 0 |
| Feb 15, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,007 | $148.06 | $149.1K | 0 |
| Feb 15, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,009 | $148.06 | $149.4K | 0 |
| Feb 1, 2024↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 1,591 | $170.99 | $272.1K | 0 |
| Dec 27, 2023↗ | BONNEY MICHAEL W | Director | Sell | 30,000 | $195.00 | $5.85M | 0 |
| Aug 3, 2023↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 7,627 | $184.78 | $1.41M | 0 |
| Aug 3, 2023↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 4,057 | $185.85 | $754.0K | 0 |
| Aug 3, 2023↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 3,460 | $185.85 | $643.0K | 0 |
| Aug 3, 2023↗ | Vaishnaw Akshay | President | Sell | 4,057 | $185.85 | $754.0K | 0 |
| Aug 2, 2023↗ | BONNEY MICHAEL W | Director | Sell | 6,448 | $185.38 | $1.20M | 0 |
| Apr 26, 2023↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 4,294 | $197.12 | $846.5K | 0 |
| Apr 26, 2023↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 7,615 | $194.59 | $1.48M | 0 |
| Apr 26, 2023↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 977 | $194.59 | $190.1K | 0 |
| Apr 26, 2023↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,476 | $194.59 | $287.2K | 0 |
| Apr 26, 2023↗ | Vaishnaw Akshay | President | Sell | 2,392 | $194.59 | $465.5K | 0 |
| Apr 6, 2023↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 3,500 | $210.00 | $735.0K | 0 |
| Mar 3, 2023↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 18,072 | $200.00 | $3.61M | 0 |
| Feb 10, 2023↗ | Vaishnaw Akshay | President | Sell | 38,044 | $215.97 | $8.22M | 0 |
| Feb 1, 2023↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 1,675 | $226.01 | $378.6K | 0 |
| Feb 1, 2023↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 5,025 | $230.19 | $1.16M | 0 |
| Dec 5, 2022↗ | Vaishnaw Akshay | President | Sell | 1,324 | $226.20 | $299.5K | 0 |
| Nov 21, 2022↗ | Ausiello Dennis A | Director | Sell | 22,500 | $220.00 | $4.95M | 0 |
| Aug 15, 2022↗ | SHARP PHILLIP A | Director | Sell | 33,670 | $230.49 | $7.76M | 0 |
| Aug 3, 2022↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 5,086 | $191.55 | $974.2K | 0 |
| Aug 3, 2022↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 6,002 | $191.68 | $1.15M | 0 |
| Aug 3, 2022↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 5,054 | $191.69 | $968.8K | 0 |
| Aug 3, 2022↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 5,383 | $206.72 | $1.11M | 0 |
| Aug 3, 2022↗ | Vaishnaw Akshay | President | Sell | 6,052 | $191.73 | $1.16M | 0 |
| Jul 5, 2022↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,754 | $150.00 | $263.1K | 0 |
| Apr 1, 2022↗ | PAUL STEVEN M | Director | Sell | 15,000 | $170.69 | $2.56M | 0 |
| Feb 9, 2022↗ | SHARP PHILLIP A | Director | Sell | 30,000 | $150.00 | $4.50M | 0 |
| Feb 1, 2022↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,518 | $144.67 | $219.6K | 0 |
| Dec 21, 2021↗ | Greenstreet Yvonne | President & COO | Sell | 2,538 | $189.01 | $479.7K | 0 |
| Dec 21, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 6,636 | $188.98 | $1.25M | 0 |
| Dec 21, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 5,417 | $190.03 | $1.03M | 0 |
| Nov 12, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,978 | $171.52 | $5.83M | 0 |
| Aug 13, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,979 | $199.78 | $6.79M | 0 |
| Aug 9, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 10,834 | $200.00 | $2.17M | 0 |
| Aug 6, 2021↗ | Greenstreet Yvonne | President & COO | Sell | 53,064 | $199.00 | $10.56M | 0 |
| Aug 5, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 10,000 | $188.95 | $1.89M | 0 |
| Jul 12, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 6,812 | $178.96 | $1.22M | 0 |
| Jun 18, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 14,708 | $175.00 | $2.57M | 0 |
| Jun 9, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 1,734 | $154.00 | $267.0K | 0 |
| May 13, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,979 | $130.78 | $4.44M | 0 |
| Apr 19, 2021↗ | Greenstreet Yvonne | President & COO | Sell | 2,351 | $131.85 | $310.0K | 0 |
| Apr 19, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 2,089 | $131.85 | $275.4K | 0 |
| Apr 19, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 7,507 | $131.85 | $989.8K | 0 |
| Apr 19, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 8,789 | $135.89 | $1.19M | 0 |
| Feb 24, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,979 | $147.31 | $5.01M | 0 |
| Oct 10, 2019↗ | Poulton Jeffrey V. | Chief Financial Officer | Sell | 1,383 | $131.85 | $182.3K | 0 |
ALNY Insider Buying Activity
The following table shows recent insider purchases of Alnylam Pharmaceuticals, Inc. (ALNY) stock reported via SEC Form 4 filings.
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Aug 29, 2024↗ | Reitan Colleen F | Director | Buy | 36 | $287.85 | $10.4K | 0 |
ALNY Insider Selling Activity
The following table shows recent insider sales of Alnylam Pharmaceuticals, Inc. (ALNY) stock reported via SEC Form 4 filings.
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Mar 6, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 1,291 | $323.54 | $417.7K | 21,831 |
| Mar 6, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 4,713 | $323.53 | $1.52M | 23,300 |
| Mar 6, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 2,933 | $323.08 | $947.6K | 98,493 |
| Mar 6, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 2,468 | $323.08 | $797.4K | 64,159 |
| Mar 6, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 2,309 | $323.08 | $746.0K | 36,500 |
| Mar 4, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 6,500 | $323.62 | $2.10M | 25,063 |
| Mar 4, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 6,984 | $323.63 | $2.26M | 26,848 |
| Mar 4, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 13,598 | $327.65 | $4.46M | 105,227 |
| Mar 4, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 4,412 | $327.65 | $1.45M | 66,414 |
| Mar 4, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 3,196 | $327.65 | $1.05M | 38,157 |
| Mar 2, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 4,627 | $331.34 | $1.53M | 26,629 |
| Feb 17, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 4,000 | $321.25 | $1.28M | 23,305 |
| Feb 17, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 2,242 | $310.08 | $695.2K | 24,848 |
| Feb 17, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 13,916 | $310.08 | $4.32M | 85,662 |
| Feb 17, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 2,242 | $310.08 | $695.2K | 59,802 |
| Feb 17, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 1,959 | $310.08 | $607.4K | 31,769 |
| Feb 12, 2026↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 4,000 | $321.25 | $1.28M | 0 |
| Feb 12, 2026↗ | Garg Pushkal | EVP Chief R&D | Sell | 2,242 | $310.08 | $695.2K | 0 |
| Feb 12, 2026↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 2,242 | $310.08 | $695.2K | 0 |
| Feb 12, 2026↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,959 | $310.08 | $607.4K | 0 |
| Jan 14, 2026↗ | Fitzgerald Kevin Joseph | officer: CSO & EVP, Head of Research | Sell | 3,740 | $367.35 | $1.37M | 25,025 |
| Jan 14, 2026↗ | Garg Pushkal | officer: EVP Chief R&D | Sell | 1,469 | $362.74 | $532.9K | 23,982 |
| Jan 14, 2026↗ | Greenstreet Yvonne | director, officer: Chief Executive Officer | Sell | 9,459 | $362.71 | $3.43M | 87,741 |
| Jan 14, 2026↗ | Poulton Jeffrey V. | officer: EVP, Chief Financial Officer | Sell | 2,704 | $363.06 | $981.7K | 60,173 |
| Jan 14, 2026↗ | Tanguler Tolga | officer: EVP, Chief Commercial Officer | Sell | 1,450 | $362.57 | $525.7K | 31,199 |
| Jan 11, 2026↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 3,800 | $367.37 | $1.40M | 0 |
| Jan 11, 2026↗ | Garg Pushkal | EVP Chief R&D | Sell | 1,510 | $362.87 | $547.9K | 0 |
| Jan 11, 2026↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 9,577 | $362.87 | $3.48M | 0 |
| Jan 11, 2026↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 2,780 | $362.87 | $1.01M | 0 |
| Jan 11, 2026↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,510 | $362.87 | $547.9K | 0 |
| Nov 26, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 1,121 | $445.12 | $499.0K | 0 |
| Nov 17, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 12,128 | $452.18 | $5.48M | 0 |
| Nov 12, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 25,650 | $452.75 | $11.61M | 0 |
| Oct 1, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 2,441 | $452.05 | $1.10M | 0 |
| Oct 1, 2025↗ | Garg Pushkal | EVP Chief R&D | Sell | 5,959 | $451.76 | $2.69M | 0 |
| Oct 1, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 8,924 | $452.05 | $4.03M | 0 |
| Oct 1, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 3,821 | $452.05 | $1.73M | 0 |
| Oct 1, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,405 | $452.05 | $635.1K | 0 |
| Sep 9, 2025↗ | Reitan Colleen F | Director | Sell | 18,000 | $467.60 | $8.42M | 0 |
| Aug 29, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 3,474 | $448.37 | $1.56M | 0 |
| Aug 18, 2025↗ | BONNEY MICHAEL W | Director | Sell | 11,250 | $450.00 | $5.06M | 0 |
| Aug 15, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 1,396 | $453.27 | $632.8K | 0 |
| Aug 15, 2025↗ | Garg Pushkal | EVP Chief R&D | Sell | 2,851 | $455.89 | $1.30M | 0 |
| Aug 15, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 6,979 | $453.27 | $3.16M | 0 |
| Aug 15, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 2,274 | $453.27 | $1.03M | 0 |
| Aug 15, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,396 | $453.27 | $632.8K | 0 |
| Aug 14, 2025↗ | Ausiello Dennis A | Director | Sell | 31,448 | $436.58 | $13.73M | 0 |
| May 30, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 50,937 | $305.00 | $15.54M | 0 |
| May 15, 2025↗ | BONNEY MICHAEL W | Director | Sell | 11,250 | $277.71 | $3.12M | 0 |
| Mar 24, 2025↗ | PYOTT DAVID E I | Director | Sell | 7,440 | $299.00 | $2.22M | 0 |
| Mar 21, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 9,766 | $293.36 | $2.86M | 0 |
| Mar 3, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 2,755 | $242.94 | $669.3K | 0 |
| Mar 3, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 2,557 | $242.92 | $621.1K | 0 |
| Mar 3, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 3,877 | $243.79 | $945.2K | 0 |
| Mar 3, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,264 | $243.78 | $308.1K | 0 |
| Mar 3, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 471 | $243.78 | $114.8K | 0 |
| Feb 28, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 496 | $241.69 | $119.9K | 0 |
| Feb 27, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 935 | $241.69 | $226.0K | 0 |
| Feb 27, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 2,900 | $241.69 | $700.9K | 0 |
| Feb 27, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 796 | $241.70 | $192.4K | 0 |
| Feb 27, 2025↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 513 | $241.68 | $124.0K | 0 |
| Feb 13, 2025↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 2,103 | $252.71 | $531.4K | 0 |
| Feb 13, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 3,109 | $253.43 | $787.9K | 0 |
| Feb 13, 2025↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 1,213 | $255.17 | $309.5K | 0 |
| Feb 13, 2025↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 967 | $255.17 | $246.8K | 0 |
| Jan 27, 2025↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 52,592 | $285.00 | $14.99M | 0 |
| Jan 23, 2025↗ | SHARP PHILLIP A | Director | Sell | 11,250 | $275.00 | $3.09M | 0 |
| Dec 12, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 1,752 | $251.00 | $439.8K | 0 |
| Nov 25, 2024↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 3,000 | $251.65 | $754.9K | 0 |
| Nov 25, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 1,682 | $250.98 | $422.1K | 0 |
| Nov 25, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 5,219 | $250.98 | $1.31M | 0 |
| Nov 25, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,682 | $250.98 | $422.1K | 0 |
| Nov 25, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,469 | $250.98 | $368.7K | 0 |
| Aug 29, 2024↗ | Reitan Colleen F | Director | Sell | 36 | $232.86 | $8.4K | 0 |
| Aug 20, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 15,000 | $280.00 | $4.20M | 0 |
| Aug 12, 2024↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 22,025 | $270.99 | $5.97M | 0 |
| Aug 6, 2024↗ | Ausiello Dennis A | Director | Sell | 20,250 | $262.00 | $5.31M | 0 |
| Aug 1, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 15,148 | $270.00 | $4.09M | 0 |
| Jul 11, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 7,093 | $261.00 | $1.85M | 0 |
| Jun 25, 2024↗ | SCHULMAN AMY W | Director | Sell | 8,500 | $240.00 | $2.04M | 0 |
| Jun 24, 2024↗ | Fitzgerald Kevin Joseph | CSO & EVP, Head of Research | Sell | 1,198 | $230.99 | $276.7K | 0 |
| Jun 24, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 2,103 | $230.99 | $485.8K | 0 |
| Jun 24, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 8,301 | $230.99 | $1.92M | 0 |
| Jun 24, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,605 | $231.00 | $370.7K | 0 |
| Jun 24, 2024↗ | PYOTT DAVID E I | Director | Sell | 32,450 | $220.69 | $7.16M | 0 |
| Jun 24, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,605 | $231.00 | $370.7K | 0 |
| May 29, 2024↗ | SCHULMAN AMY W | Director | Sell | 21,700 | $148.60 | $3.22M | 0 |
| Feb 29, 2024↗ | SHARP PHILLIP A | Director | Sell | 30,000 | $151.34 | $4.54M | 0 |
| Feb 27, 2024↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 329 | $155.30 | $51.1K | 0 |
| Feb 27, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 574 | $155.30 | $89.1K | 0 |
| Feb 27, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 2,932 | $155.31 | $455.4K | 0 |
| Feb 27, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 574 | $155.30 | $89.1K | 0 |
| Feb 27, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 501 | $155.30 | $77.8K | 0 |
| Feb 15, 2024↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 1,308 | $148.06 | $193.7K | 0 |
| Feb 15, 2024↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 7,030 | $148.06 | $1.04M | 0 |
| Feb 15, 2024↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 1,007 | $148.06 | $149.1K | 0 |
| Feb 15, 2024↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,009 | $148.06 | $149.4K | 0 |
| Feb 1, 2024↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 1,591 | $170.99 | $272.1K | 0 |
| Dec 27, 2023↗ | BONNEY MICHAEL W | Director | Sell | 30,000 | $195.00 | $5.85M | 0 |
| Aug 3, 2023↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 7,627 | $184.78 | $1.41M | 0 |
| Aug 3, 2023↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 4,057 | $185.85 | $754.0K | 0 |
| Aug 3, 2023↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 3,460 | $185.85 | $643.0K | 0 |
| Aug 3, 2023↗ | Vaishnaw Akshay | President | Sell | 4,057 | $185.85 | $754.0K | 0 |
| Aug 2, 2023↗ | BONNEY MICHAEL W | Director | Sell | 6,448 | $185.38 | $1.20M | 0 |
| Apr 26, 2023↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 4,294 | $197.12 | $846.5K | 0 |
| Apr 26, 2023↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 7,615 | $194.59 | $1.48M | 0 |
| Apr 26, 2023↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 977 | $194.59 | $190.1K | 0 |
| Apr 26, 2023↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,476 | $194.59 | $287.2K | 0 |
| Apr 26, 2023↗ | Vaishnaw Akshay | President | Sell | 2,392 | $194.59 | $465.5K | 0 |
| Apr 6, 2023↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 3,500 | $210.00 | $735.0K | 0 |
| Mar 3, 2023↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 18,072 | $200.00 | $3.61M | 0 |
| Feb 10, 2023↗ | Vaishnaw Akshay | President | Sell | 38,044 | $215.97 | $8.22M | 0 |
| Feb 1, 2023↗ | Franchini Indrani Lall | EVP, CLO & Secretary | Sell | 1,675 | $226.01 | $378.6K | 0 |
| Feb 1, 2023↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 5,025 | $230.19 | $1.16M | 0 |
| Dec 5, 2022↗ | Vaishnaw Akshay | President | Sell | 1,324 | $226.20 | $299.5K | 0 |
| Nov 21, 2022↗ | Ausiello Dennis A | Director | Sell | 22,500 | $220.00 | $4.95M | 0 |
| Aug 15, 2022↗ | SHARP PHILLIP A | Director | Sell | 33,670 | $230.49 | $7.76M | 0 |
| Aug 3, 2022↗ | Garg Pushkal | CMO & EVP Dev & Med Affairs | Sell | 5,086 | $191.55 | $974.2K | 0 |
| Aug 3, 2022↗ | Greenstreet Yvonne | Chief Executive Officer | Sell | 6,002 | $191.68 | $1.15M | 0 |
| Aug 3, 2022↗ | Poulton Jeffrey V. | EVP, Chief Financial Officer | Sell | 5,054 | $191.69 | $968.8K | 0 |
| Aug 3, 2022↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 5,383 | $206.72 | $1.11M | 0 |
| Aug 3, 2022↗ | Vaishnaw Akshay | President | Sell | 6,052 | $191.73 | $1.16M | 0 |
| Jul 5, 2022↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,754 | $150.00 | $263.1K | 0 |
| Apr 1, 2022↗ | PAUL STEVEN M | Director | Sell | 15,000 | $170.69 | $2.56M | 0 |
| Feb 9, 2022↗ | SHARP PHILLIP A | Director | Sell | 30,000 | $150.00 | $4.50M | 0 |
| Feb 1, 2022↗ | Tanguler Tolga | EVP, Chief Commercial Officer | Sell | 1,518 | $144.67 | $219.6K | 0 |
| Dec 21, 2021↗ | Greenstreet Yvonne | President & COO | Sell | 2,538 | $189.01 | $479.7K | 0 |
| Dec 21, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 6,636 | $188.98 | $1.25M | 0 |
| Dec 21, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 5,417 | $190.03 | $1.03M | 0 |
| Nov 12, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,978 | $171.52 | $5.83M | 0 |
| Aug 13, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,979 | $199.78 | $6.79M | 0 |
| Aug 9, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 10,834 | $200.00 | $2.17M | 0 |
| Aug 6, 2021↗ | Greenstreet Yvonne | President & COO | Sell | 53,064 | $199.00 | $10.56M | 0 |
| Aug 5, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 10,000 | $188.95 | $1.89M | 0 |
| Jul 12, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 6,812 | $178.96 | $1.22M | 0 |
| Jun 18, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 14,708 | $175.00 | $2.57M | 0 |
| Jun 9, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 1,734 | $154.00 | $267.0K | 0 |
| May 13, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,979 | $130.78 | $4.44M | 0 |
| Apr 19, 2021↗ | Greenstreet Yvonne | President & COO | Sell | 2,351 | $131.85 | $310.0K | 0 |
| Apr 19, 2021↗ | KEATING LAURIE | EVP, Chief Legal Officer | Sell | 2,089 | $131.85 | $275.4K | 0 |
| Apr 19, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 7,507 | $131.85 | $989.8K | 0 |
| Apr 19, 2021↗ | Vaishnaw Akshay | President, R&D | Sell | 8,789 | $135.89 | $1.19M | 0 |
| Feb 24, 2021↗ | MARAGANORE JOHN | Chief Executive Officer | Sell | 33,979 | $147.31 | $5.01M | 0 |
| Oct 10, 2019↗ | Poulton Jeffrey V. | Chief Financial Officer | Sell | 1,383 | $131.85 | $182.3K | 0 |
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