IONS
HealthcareIonis Pharmaceuticals, Inc.
$71.40-0.93 (-1.28%)
Prev Close
$72.33
Open
$71.84
High
$72.30
Low
$70.92
Volume
1.41M
Market Cap
$11.76B
P/E
—
Div Yield
—
Over the past 12 months, insider activity at Ionis Pharmaceuticals, Inc. (IONS) has been dominated by selling, with 1 insider purchase totaling $477.9K and 94 insider sales totaling $142.46M. The most recent insider transaction was by Baroldi Joseph (officer: EVP, Chief Business Officer), who sold $511.9K worth of shares on Mar 5, 2026. Ionis Pharmaceuticals, Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $11.76B.
Buys (12M)
1
$477.9K
Sells (12M)
94
$142.46M
Net Activity
Net Seller
$141.99M
Active Insiders
19
last 12 mo
IONS Price Chart
IONS Insider Trading Activity
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Mar 5, 2026↗ | Baroldi Joseph | officer: EVP, Chief Business Officer | Sell | 6,421 | $79.73 | $511.9K | 41,317 |
| Mar 5, 2026↗ | BENNETT C FRANK | officer: EVP, Chief Scientific Officer | Sell | 85,089 | $79.23 | $6.74M | 94,043 |
| Mar 5, 2026↗ | Devers Shannon L. | officer: EVP, Chief Human Resources Ofc | Sell | 20,106 | $79.40 | $1.60M | 28,326 |
| Mar 5, 2026↗ | Diaz Allene M. | director | Sell | 54,878 | $79.35 | $4.35M | 19,424 |
| Mar 5, 2026↗ | KLEIN JOSEPH III | director | Sell | 21,332 | $79.51 | $1.70M | 18,820 |
| Mar 5, 2026↗ | LOSCALZO JOSEPH | director | Sell | 1,032 | $80.26 | $82.8K | 36,330 |
| Feb 13, 2026↗ | PARSHALL B LYNNE | director | Sell | 5,000 | $82.72 | $413.6K | 56,344 |
| Feb 13, 2026↗ | Swayze Eric | officer: EVP Research | Sell | 31,284 | $81.76 | $2.56M | 38,312 |
| Feb 11, 2026↗ | PARSHALL B LYNNE | Director | Sell | 5,000 | $82.72 | $413.6K | 0 |
| Feb 10, 2026↗ | Monia Brett P | director, officer: Chief Executive Officer | Sell | 29,430 | $85.79 | $2.52M | 254,497 |
| Feb 6, 2026↗ | Monia Brett P | Chief Executive Officer | Sell | 29,430 | $85.79 | $2.52M | 0 |
| Feb 4, 2026↗ | BENNETT C FRANK | officer: EVP, Chief Scientific Officer | Sell | 36,463 | $82.79 | $3.02M | 80,293 |
| Feb 2, 2026↗ | Baroldi Joseph | officer: EVP, Chief Business Officer | Sell | 5,296 | $82.96 | $439.4K | 45,413 |
| Feb 2, 2026↗ | BENNETT C FRANK | officer: EVP, Chief Scientific Officer | Sell | 90,974 | $82.93 | $7.54M | 100,293 |
| Feb 2, 2026↗ | Birchler Brian | officer: EVP, Corp and Development Ops | Sell | 6,179 | $83.03 | $513.0K | 66,247 |
| Feb 2, 2026↗ | HOUGEN ELIZABETH L | officer: EVP, Finance & CFO | Sell | 6,988 | $83.24 | $581.7K | 132,881 |
| Feb 2, 2026↗ | Monia Brett P | director, officer: Chief Executive Officer | Sell | 62,970 | $82.72 | $5.21M | 283,927 |
| Feb 2, 2026↗ | O'NEIL PATRICK R. | officer: EVP CLO & General Counsel | Sell | 6,179 | $83.53 | $516.2K | 71,983 |
| Feb 2, 2026↗ | Schneider Eugene | officer: EVP, Chf Clinical Develop Ofcr | Sell | 6,179 | $83.45 | $515.6K | 69,702 |
| Feb 2, 2026↗ | Swayze Eric | officer: EVP Research | Sell | 6,179 | $82.93 | $512.4K | 47,747 |
| Jan 29, 2026↗ | Baroldi Joseph | EVP, Chief Business Officer | Sell | 5,296 | $82.96 | $439.4K | 0 |
| Jan 29, 2026↗ | BENNETT C FRANK | EVP, Chief Scientific Officer | Sell | 5,885 | $82.95 | $488.1K | 0 |
| Jan 29, 2026↗ | Birchler Brian | EVP, Corp and Development Ops | Sell | 6,179 | $83.03 | $513.0K | 0 |
| Jan 29, 2026↗ | HOUGEN ELIZABETH L | EVP, Finance & CFO | Sell | 6,988 | $83.24 | $581.7K | 0 |
| Jan 29, 2026↗ | Monia Brett P | Chief Executive Officer | Sell | 62,970 | $82.72 | $5.21M | 0 |
| Jan 29, 2026↗ | O'NEIL PATRICK R. | EVP CLO & General Counsel | Sell | 6,179 | $83.53 | $516.2K | 0 |
| Jan 29, 2026↗ | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | Sell | 6,179 | $83.45 | $515.6K | 0 |
| Jan 29, 2026↗ | Swayze Eric | EVP Research | Sell | 6,179 | $82.93 | $512.4K | 0 |
| Jan 23, 2026↗ | Devers Shannon L. | officer: EVP, Chief Human Resources Ofc | Sell | 3,977 | $81.34 | $323.5K | 22,541 |
| Jan 22, 2026↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 3,977 | $81.34 | $323.5K | 0 |
| Jan 15, 2026↗ | Baroldi Joseph | EVP, Chief Business Officer | Sell | 8,056 | $75.75 | $610.3K | 0 |
| Jan 15, 2026↗ | BENNETT C FRANK | EVP, Chief Scientific Officer | Sell | 8,977 | $75.15 | $674.6K | 0 |
| Jan 15, 2026↗ | Birchler Brian | EVP, Corp and Development Ops | Sell | 8,480 | $75.11 | $636.9K | 0 |
| Jan 15, 2026↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 8,353 | $75.95 | $634.4K | 0 |
| Jan 15, 2026↗ | HOUGEN ELIZABETH L | EVP, Finance & CFO | Sell | 12,922 | $75.22 | $972.0K | 0 |
| Jan 15, 2026↗ | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | Sell | 1,823 | $75.96 | $138.5K | 0 |
| Jan 15, 2026↗ | Kordasiewicz Holly B. | EVP, Chief Development Officer | Sell | 4,141 | $75.66 | $313.3K | 0 |
| Jan 15, 2026↗ | Monia Brett P | Chief Executive Officer | Sell | 44,034 | $74.82 | $3.29M | 0 |
| Jan 15, 2026↗ | O'NEIL PATRICK R. | EVP CLO & General Counsel | Sell | 9,191 | $75.84 | $697.0K | 0 |
| Jan 15, 2026↗ | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | Sell | 9,302 | $75.59 | $703.1K | 0 |
| Jan 15, 2026↗ | Swayze Eric | EVP Research | Sell | 9,933 | $75.34 | $748.4K | 0 |
| Jan 7, 2026↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 44,199 | $85.08 | $3.76M | 0 |
| Jan 2, 2026↗ | Swayze Eric | EVP Research | Sell | 23,463 | $79.12 | $1.86M | 0 |
| Dec 1, 2025↗ | WENDER JOSEPH H | Director | Sell | 28,000 | $80.82 | $2.26M | 0 |
| Nov 25, 2025↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 16,777 | $80.91 | $1.36M | 0 |
| Nov 25, 2025↗ | KLEIN JOSEPH III | Director | Sell | 4,000 | $80.00 | $320.0K | 0 |
| Nov 19, 2025↗ | HERMAN JOAN E | Director | Sell | 44,000 | $72.13 | $3.17M | 0 |
| Nov 6, 2025↗ | Birchler Brian | EVP, Corp and Development Ops | Sell | 8,000 | $76.17 | $609.4K | 0 |
| Nov 5, 2025↗ | Geary Richard S | EVP, Chief Development Officer | Sell | 34,639 | $75.69 | $2.62M | 0 |
| Oct 31, 2025↗ | Geary Richard S | EVP, Chief Development Officer | Sell | 90,929 | $75.11 | $6.83M | 0 |
Showing 1–50 of 97
1 / 2
IONS Insider Buying Activity
The following table shows recent insider purchases of Ionis Pharmaceuticals, Inc. (IONS) stock reported via SEC Form 4 filings.
No insider buying activity found for IONS in the last 12 months.
IONS Insider Selling Activity
The following table shows recent insider sales of Ionis Pharmaceuticals, Inc. (IONS) stock reported via SEC Form 4 filings.
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Mar 5, 2026↗ | Baroldi Joseph | officer: EVP, Chief Business Officer | Sell | 6,421 | $79.73 | $511.9K | 41,317 |
| Mar 5, 2026↗ | BENNETT C FRANK | officer: EVP, Chief Scientific Officer | Sell | 85,089 | $79.23 | $6.74M | 94,043 |
| Mar 5, 2026↗ | Devers Shannon L. | officer: EVP, Chief Human Resources Ofc | Sell | 20,106 | $79.40 | $1.60M | 28,326 |
| Mar 5, 2026↗ | Diaz Allene M. | director | Sell | 54,878 | $79.35 | $4.35M | 19,424 |
| Mar 5, 2026↗ | KLEIN JOSEPH III | director | Sell | 21,332 | $79.51 | $1.70M | 18,820 |
| Mar 5, 2026↗ | LOSCALZO JOSEPH | director | Sell | 1,032 | $80.26 | $82.8K | 36,330 |
| Feb 13, 2026↗ | PARSHALL B LYNNE | director | Sell | 5,000 | $82.72 | $413.6K | 56,344 |
| Feb 13, 2026↗ | Swayze Eric | officer: EVP Research | Sell | 31,284 | $81.76 | $2.56M | 38,312 |
| Feb 11, 2026↗ | PARSHALL B LYNNE | Director | Sell | 5,000 | $82.72 | $413.6K | 0 |
| Feb 10, 2026↗ | Monia Brett P | director, officer: Chief Executive Officer | Sell | 29,430 | $85.79 | $2.52M | 254,497 |
| Feb 6, 2026↗ | Monia Brett P | Chief Executive Officer | Sell | 29,430 | $85.79 | $2.52M | 0 |
| Feb 4, 2026↗ | BENNETT C FRANK | officer: EVP, Chief Scientific Officer | Sell | 36,463 | $82.79 | $3.02M | 80,293 |
| Feb 2, 2026↗ | Baroldi Joseph | officer: EVP, Chief Business Officer | Sell | 5,296 | $82.96 | $439.4K | 45,413 |
| Feb 2, 2026↗ | BENNETT C FRANK | officer: EVP, Chief Scientific Officer | Sell | 90,974 | $82.93 | $7.54M | 100,293 |
| Feb 2, 2026↗ | Birchler Brian | officer: EVP, Corp and Development Ops | Sell | 6,179 | $83.03 | $513.0K | 66,247 |
| Feb 2, 2026↗ | HOUGEN ELIZABETH L | officer: EVP, Finance & CFO | Sell | 6,988 | $83.24 | $581.7K | 132,881 |
| Feb 2, 2026↗ | Monia Brett P | director, officer: Chief Executive Officer | Sell | 62,970 | $82.72 | $5.21M | 283,927 |
| Feb 2, 2026↗ | O'NEIL PATRICK R. | officer: EVP CLO & General Counsel | Sell | 6,179 | $83.53 | $516.2K | 71,983 |
| Feb 2, 2026↗ | Schneider Eugene | officer: EVP, Chf Clinical Develop Ofcr | Sell | 6,179 | $83.45 | $515.6K | 69,702 |
| Feb 2, 2026↗ | Swayze Eric | officer: EVP Research | Sell | 6,179 | $82.93 | $512.4K | 47,747 |
| Jan 29, 2026↗ | Baroldi Joseph | EVP, Chief Business Officer | Sell | 5,296 | $82.96 | $439.4K | 0 |
| Jan 29, 2026↗ | BENNETT C FRANK | EVP, Chief Scientific Officer | Sell | 5,885 | $82.95 | $488.1K | 0 |
| Jan 29, 2026↗ | Birchler Brian | EVP, Corp and Development Ops | Sell | 6,179 | $83.03 | $513.0K | 0 |
| Jan 29, 2026↗ | HOUGEN ELIZABETH L | EVP, Finance & CFO | Sell | 6,988 | $83.24 | $581.7K | 0 |
| Jan 29, 2026↗ | Monia Brett P | Chief Executive Officer | Sell | 62,970 | $82.72 | $5.21M | 0 |
| Jan 29, 2026↗ | O'NEIL PATRICK R. | EVP CLO & General Counsel | Sell | 6,179 | $83.53 | $516.2K | 0 |
| Jan 29, 2026↗ | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | Sell | 6,179 | $83.45 | $515.6K | 0 |
| Jan 29, 2026↗ | Swayze Eric | EVP Research | Sell | 6,179 | $82.93 | $512.4K | 0 |
| Jan 23, 2026↗ | Devers Shannon L. | officer: EVP, Chief Human Resources Ofc | Sell | 3,977 | $81.34 | $323.5K | 22,541 |
| Jan 22, 2026↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 3,977 | $81.34 | $323.5K | 0 |
| Jan 15, 2026↗ | Baroldi Joseph | EVP, Chief Business Officer | Sell | 8,056 | $75.75 | $610.3K | 0 |
| Jan 15, 2026↗ | BENNETT C FRANK | EVP, Chief Scientific Officer | Sell | 8,977 | $75.15 | $674.6K | 0 |
| Jan 15, 2026↗ | Birchler Brian | EVP, Corp and Development Ops | Sell | 8,480 | $75.11 | $636.9K | 0 |
| Jan 15, 2026↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 8,353 | $75.95 | $634.4K | 0 |
| Jan 15, 2026↗ | HOUGEN ELIZABETH L | EVP, Finance & CFO | Sell | 12,922 | $75.22 | $972.0K | 0 |
| Jan 15, 2026↗ | Jenne Kyle | EVP, Chf GL Pdt Str Ofcr | Sell | 1,823 | $75.96 | $138.5K | 0 |
| Jan 15, 2026↗ | Kordasiewicz Holly B. | EVP, Chief Development Officer | Sell | 4,141 | $75.66 | $313.3K | 0 |
| Jan 15, 2026↗ | Monia Brett P | Chief Executive Officer | Sell | 44,034 | $74.82 | $3.29M | 0 |
| Jan 15, 2026↗ | O'NEIL PATRICK R. | EVP CLO & General Counsel | Sell | 9,191 | $75.84 | $697.0K | 0 |
| Jan 15, 2026↗ | Schneider Eugene | EVP, Chf Clinical Develop Ofcr | Sell | 9,302 | $75.59 | $703.1K | 0 |
| Jan 15, 2026↗ | Swayze Eric | EVP Research | Sell | 9,933 | $75.34 | $748.4K | 0 |
| Jan 7, 2026↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 44,199 | $85.08 | $3.76M | 0 |
| Jan 2, 2026↗ | Swayze Eric | EVP Research | Sell | 23,463 | $79.12 | $1.86M | 0 |
| Dec 1, 2025↗ | WENDER JOSEPH H | Director | Sell | 28,000 | $80.82 | $2.26M | 0 |
| Nov 25, 2025↗ | Devers Shannon L. | EVP, Chief Human Resources Ofc | Sell | 16,777 | $80.91 | $1.36M | 0 |
| Nov 25, 2025↗ | KLEIN JOSEPH III | Director | Sell | 4,000 | $80.00 | $320.0K | 0 |
| Nov 19, 2025↗ | HERMAN JOAN E | Director | Sell | 44,000 | $72.13 | $3.17M | 0 |
| Nov 6, 2025↗ | Birchler Brian | EVP, Corp and Development Ops | Sell | 8,000 | $76.17 | $609.4K | 0 |
| Nov 5, 2025↗ | Geary Richard S | EVP, Chief Development Officer | Sell | 34,639 | $75.69 | $2.62M | 0 |
| Oct 31, 2025↗ | Geary Richard S | EVP, Chief Development Officer | Sell | 90,929 | $75.11 | $6.83M | 0 |
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