KPTI
Karyopharm Therapeutics Inc.$8.09-0.33 (-3.87%)Prev Close$8.40·MCap$72.7M·P/E—·Vol546.8K·Yield—
▲
Buys (12M)
0
$0.00
▼
Sells (12M)
22
$330.3K
◆
Net Activity
Net Seller
$330.3K
●
Active Insiders
7
last 12 mo
Over the past 12 months, insider activity at Karyopharm Therapeutics Inc. (KPTI) has been exclusively selling, with 0 insider purchases totaling $0.00 and 22 insider sales totaling $330.3K. The most recent insider transaction was by Cheng Sohanya Roshan (officer: EVP & Chief Commercial Officer), who sold $43.3K worth of shares on Mar 3, 2026. Karyopharm Therapeutics Inc. operates in the Healthcare sector, within the Biotechnology industry, with a market cap of $72.7M.
KPTI Insider Trading Activity
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Mar 3, 2026 | Cheng Sohanya Roshan | officer: EVP & Chief Commercial Officer | Sell | 4,604 | $9.41 | $43.3K | 107,317 |
| Mar 3, 2026 | Mano Michael | officer: EVP, CLO&Secretary | Sell | 3,526 | $9.41 | $33.2K | 93,964 |
| Mar 3, 2026 | Paulson Richard A. | director, officer: President and CEO | Sell | 12,361 | $9.41 | $116.3K | 267,030 |
| Mar 3, 2026 | Poulton Stuart | officer: EVP, Chief Development Officer | Sell | 5,101 | $9.41 | $48.0K | 94,328 |
| Mar 3, 2026 | Rangwala Reshma | officer: EVP & Chief Medical Officer | Sell | 5,066 | $9.41 | $47.7K | 56,739 |
| Feb 17, 2026 | Poulton Stuart | EVP, Chief Development Officer | Sell | 378 | $8.63 | $3.3K | 0 |
| Feb 4, 2026 | Macomber Lori | officer: EVP, CFO & Treasurer | Sell | 1,626 | $6.30 | $10.2K | 85,105 |
| Jan 29, 2026 | Abate Kristin | officer: Chief Accounting Officer | Sell | 50 | $7.03 | $351.50 | 22,622 |
| Jan 22, 2026 | Abate Kristin | officer: Chief Accounting Officer | Sell | 265 | $5.96 | $1.6K | 22,580 |
| Oct 3, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 362 | $6.30 | $2.3K | 10,046 |
| Sep 16, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 23 | $6.43 | $147.89 | 10,408 |
| Sep 16, 2025 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | 325 | $6.43 | $2.1K | 35,856 |
| Sep 16, 2025 | Mano Michael | SVP, General Counsel&Secretary | Sell | 234 | $6.43 | $1.5K | 21,425 |
| Sep 16, 2025 | Paulson Richard A. | President and CEO | Sell | 1,257 | $6.43 | $8.1K | 84,046 |
| Sep 16, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 401 | $6.43 | $2.6K | 27,710 |
| Sep 16, 2025 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 408 | $6.43 | $2.6K | 29,390 |
| Sep 4, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 12 | $6.78 | $81.36 | 9,463 |
| Jul 30, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 191 | $4.37 | $834.67 | 27,223 |
| Jul 23, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 238 | $4.00 | $952.00 | 9,475 |
| May 7, 2025 | Paulson Richard A. | President and CEO | Sell | 236 | $7.12 | $1.7K | 82,503 |
| Apr 24, 2025 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 419 | $6.17 | $2.6K | 28,853 |
| Apr 7, 2025 | Paulson Richard A. | President and CEO | Sell | 245 | $3.74 | $916.30 | 82,739 |
| Mar 6, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 571 | $6.29 | $3.6K | 9,713 |
| Mar 6, 2025 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | 3,445 | $6.29 | $21.7K | 34,314 |
| Mar 6, 2025 | Mano Michael | SVP, General Counsel&Secretary | Sell | 2,793 | $6.29 | $17.6K | 21,047 |
| Mar 6, 2025 | Paulson Richard A. | President and CEO | Sell | 11,694 | $6.29 | $73.6K | 82,984 |
| Mar 6, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 3,548 | $6.29 | $22.3K | 27,414 |
| Mar 6, 2025 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 3,587 | $6.29 | $22.6K | 29,272 |
| Feb 19, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 5,914 | $0.63 | $3.7K | 320,714 |
| Feb 5, 2025 | Paulson Richard A. | President and CEO | Sell | 4,099 | $0.65 | $2.7K | 1,120,158 |
| Jan 7, 2025 | Paulson Richard A. | President and CEO | Sell | 4,055 | $0.78 | $3.2K | 1,124,257 |
| Dec 5, 2024 | Paulson Richard A. | President and CEO | Sell | 3,620 | $0.81 | $2.9K | 1,128,312 |
| Nov 6, 2024 | Paulson Richard A. | President and CEO | Sell | 3,675 | $0.91 | $3.3K | 1,131,932 |
| Oct 7, 2024 | Paulson Richard A. | President and CEO | Sell | 3,607 | $0.88 | $3.2K | 1,135,607 |
| Sep 5, 2024 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | 5,356 | $0.72 | $3.9K | 404,051 |
| Sep 5, 2024 | Mano Michael | SVP, General Counsel&Secretary | Sell | 3,971 | $0.72 | $2.9K | 273,881 |
| Sep 5, 2024 | Mason Michael | EVP, CFO & Treasurer | Sell | 7,050 | $0.72 | $5.1K | 391,054 |
| Sep 5, 2024 | Paulson Richard A. | President and CEO | Sell | 3,667 | $0.72 | $2.6K | 1,139,214 |
| Aug 8, 2024 | Paulson Richard A. | President and CEO | Sell | 3,608 | $0.93 | $3.4K | 1,142,881 |
| Jul 31, 2024 | Poulton Stuart | EVP, Chief Development Officer | Sell | 2,883 | $1.06 | $3.1K | 326,628 |
| Jul 9, 2024 | Paulson Richard A. | President and CEO | Sell | 3,616 | $0.85 | $3.1K | 1,146,489 |
| Jun 7, 2024 | PAKIANATHAN DEEPIKA | Sell | 818,044 | $0.96 | $785.0K | 346,615 | |
| Jun 6, 2024 | Mason Michael | EVP, CFO & Treasurer | Sell | 652 | $0.99 | $645.48 | 398,104 |
| Jun 6, 2024 | Paulson Richard A. | President and CEO | Sell | 3,592 | $0.99 | $3.6K | 1,150,105 |
| Jun 4, 2024 | PAKIANATHAN DEEPIKA | Sell | 906,178 | $0.97 | $880.7K | 1,505,131 | |
| May 7, 2024 | Paulson Richard A. | President and CEO | Sell | 3,576 | $1.13 | $4.0K | 1,153,697 |
| Apr 23, 2024 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 6,789 | $1.17 | $7.9K | 342,931 |
| Apr 5, 2024 | Paulson Richard A. | President and CEO | Sell | 3,563 | $1.29 | $4.6K | 1,157,273 |
| Mar 6, 2024 | Paulson Richard A. | President and CEO | Sell | 3,573 | $1.30 | $4.6K | 1,160,836 |
| Feb 29, 2024 | Mason Michael | EVP, CFO & Treasurer | Sell | 2,545 | $1.32 | $3.4K | 244,400 |
Showing 1–50 of 108
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KPTI Insider Buying Activity
The following table shows recent insider purchases of Karyopharm Therapeutics Inc. (KPTI) stock reported via SEC Form 4 filings.
No insider buying activity found for KPTI in the last 12 months.
KPTI Insider Selling Activity
The following table shows recent insider sales of Karyopharm Therapeutics Inc. (KPTI) stock reported via SEC Form 4 filings.
| Date | Insider | Role | Type | Shares | Avg Price | Value | Shares After |
|---|---|---|---|---|---|---|---|
| Mar 3, 2026 | Cheng Sohanya Roshan | officer: EVP & Chief Commercial Officer | Sell | 4,604 | $9.41 | $43.3K | 107,317 |
| Mar 3, 2026 | Mano Michael | officer: EVP, CLO&Secretary | Sell | 3,526 | $9.41 | $33.2K | 93,964 |
| Mar 3, 2026 | Paulson Richard A. | director, officer: President and CEO | Sell | 12,361 | $9.41 | $116.3K | 267,030 |
| Mar 3, 2026 | Poulton Stuart | officer: EVP, Chief Development Officer | Sell | 5,101 | $9.41 | $48.0K | 94,328 |
| Mar 3, 2026 | Rangwala Reshma | officer: EVP & Chief Medical Officer | Sell | 5,066 | $9.41 | $47.7K | 56,739 |
| Feb 17, 2026 | Poulton Stuart | EVP, Chief Development Officer | Sell | 378 | $8.63 | $3.3K | 0 |
| Feb 4, 2026 | Macomber Lori | officer: EVP, CFO & Treasurer | Sell | 1,626 | $6.30 | $10.2K | 85,105 |
| Jan 29, 2026 | Abate Kristin | officer: Chief Accounting Officer | Sell | 50 | $7.03 | $351.50 | 22,622 |
| Jan 22, 2026 | Abate Kristin | officer: Chief Accounting Officer | Sell | 265 | $5.96 | $1.6K | 22,580 |
| Oct 3, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 362 | $6.30 | $2.3K | 10,046 |
| Sep 16, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 23 | $6.43 | $147.89 | 10,408 |
| Sep 16, 2025 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | 325 | $6.43 | $2.1K | 35,856 |
| Sep 16, 2025 | Mano Michael | SVP, General Counsel&Secretary | Sell | 234 | $6.43 | $1.5K | 21,425 |
| Sep 16, 2025 | Paulson Richard A. | President and CEO | Sell | 1,257 | $6.43 | $8.1K | 84,046 |
| Sep 16, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 401 | $6.43 | $2.6K | 27,710 |
| Sep 16, 2025 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 408 | $6.43 | $2.6K | 29,390 |
| Sep 4, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 12 | $6.78 | $81.36 | 9,463 |
| Jul 30, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 191 | $4.37 | $834.67 | 27,223 |
| Jul 23, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 238 | $4.00 | $952.00 | 9,475 |
| May 7, 2025 | Paulson Richard A. | President and CEO | Sell | 236 | $7.12 | $1.7K | 82,503 |
| Apr 24, 2025 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 419 | $6.17 | $2.6K | 28,853 |
| Apr 7, 2025 | Paulson Richard A. | President and CEO | Sell | 245 | $3.74 | $916.30 | 82,739 |
| Mar 6, 2025 | Abate Kristin | Chief Accounting Officer | Sell | 571 | $6.29 | $3.6K | 9,713 |
| Mar 6, 2025 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | 3,445 | $6.29 | $21.7K | 34,314 |
| Mar 6, 2025 | Mano Michael | SVP, General Counsel&Secretary | Sell | 2,793 | $6.29 | $17.6K | 21,047 |
| Mar 6, 2025 | Paulson Richard A. | President and CEO | Sell | 11,694 | $6.29 | $73.6K | 82,984 |
| Mar 6, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 3,548 | $6.29 | $22.3K | 27,414 |
| Mar 6, 2025 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 3,587 | $6.29 | $22.6K | 29,272 |
| Feb 19, 2025 | Poulton Stuart | EVP, Chief Development Officer | Sell | 5,914 | $0.63 | $3.7K | 320,714 |
| Feb 5, 2025 | Paulson Richard A. | President and CEO | Sell | 4,099 | $0.65 | $2.7K | 1,120,158 |
| Jan 7, 2025 | Paulson Richard A. | President and CEO | Sell | 4,055 | $0.78 | $3.2K | 1,124,257 |
| Dec 5, 2024 | Paulson Richard A. | President and CEO | Sell | 3,620 | $0.81 | $2.9K | 1,128,312 |
| Nov 6, 2024 | Paulson Richard A. | President and CEO | Sell | 3,675 | $0.91 | $3.3K | 1,131,932 |
| Oct 7, 2024 | Paulson Richard A. | President and CEO | Sell | 3,607 | $0.88 | $3.2K | 1,135,607 |
| Sep 5, 2024 | Cheng Sohanya Roshan | EVP & Chief Commercial Officer | Sell | 5,356 | $0.72 | $3.9K | 404,051 |
| Sep 5, 2024 | Mano Michael | SVP, General Counsel&Secretary | Sell | 3,971 | $0.72 | $2.9K | 273,881 |
| Sep 5, 2024 | Mason Michael | EVP, CFO & Treasurer | Sell | 7,050 | $0.72 | $5.1K | 391,054 |
| Sep 5, 2024 | Paulson Richard A. | President and CEO | Sell | 3,667 | $0.72 | $2.6K | 1,139,214 |
| Aug 8, 2024 | Paulson Richard A. | President and CEO | Sell | 3,608 | $0.93 | $3.4K | 1,142,881 |
| Jul 31, 2024 | Poulton Stuart | EVP, Chief Development Officer | Sell | 2,883 | $1.06 | $3.1K | 326,628 |
| Jul 9, 2024 | Paulson Richard A. | President and CEO | Sell | 3,616 | $0.85 | $3.1K | 1,146,489 |
| Jun 7, 2024 | PAKIANATHAN DEEPIKA | Sell | 818,044 | $0.96 | $785.0K | 346,615 | |
| Jun 6, 2024 | Mason Michael | EVP, CFO & Treasurer | Sell | 652 | $0.99 | $645.48 | 398,104 |
| Jun 6, 2024 | Paulson Richard A. | President and CEO | Sell | 3,592 | $0.99 | $3.6K | 1,150,105 |
| Jun 4, 2024 | PAKIANATHAN DEEPIKA | Sell | 906,178 | $0.97 | $880.7K | 1,505,131 | |
| May 7, 2024 | Paulson Richard A. | President and CEO | Sell | 3,576 | $1.13 | $4.0K | 1,153,697 |
| Apr 23, 2024 | Rangwala Reshma | EVP & Chief Medical Officer | Sell | 6,789 | $1.17 | $7.9K | 342,931 |
| Apr 5, 2024 | Paulson Richard A. | President and CEO | Sell | 3,563 | $1.29 | $4.6K | 1,157,273 |
| Mar 6, 2024 | Paulson Richard A. | President and CEO | Sell | 3,573 | $1.30 | $4.6K | 1,160,836 |
| Feb 29, 2024 | Mason Michael | EVP, CFO & Treasurer | Sell | 2,545 | $1.32 | $3.4K | 244,400 |
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